ea0090p678 | Pituitary and Neuroendocrinology | ECE2023
Eda Ertorer Melek
, Tuncer Feyza
, Ciftci Sema
, Tanrikulu Seher
, Soyluk Selcukbiricik Ozlem
, Topaloğlu Omercan
, Evran Mehtap
, Kadioglu Pinar
, Aydin Sevcan
, Can Bulent
, Sehit Canan
, Pekkolay Zafer
, Oruk Gonca
, Cetinarslan Berrin
, Yarman Sema
Objective: Hereditary pituitary adenomas (PAs) are rare and occur either isolated or as part of a syndrome. Familial isolated pituitary adenoma (FIPA) is the presence of only PA in at least two members of a family, where Aryl hydrocarbon receptor interacting protein-AIP gene mutations have been identified in 10-20% of cases. However, the cause of tumorigenesis in the majority is unknown. We aimed to identify novel genetic variants in a cohort of FIPA patie...